- Started fasting all day Thurs. Jello,coffee,and Sprite. Took the first dose of suprep at 6:00 pm. 6 ounces of prep mixed with 10 ounces cold water. Drank it down in 3 swigs.Then 32 ounces cold water in one hour. Repeat this procedure at 4:00 am. THe suprep is much more tolerable tha the gallon jug of colyte I have used before. Disposable/flushable wipes are the key. He removed somepolyps and I see the doctor in a few weeks for a follow up appt. Glad its over but the suprep makes the procedure a little more tolerable.