Pretty weird comparison there, but speaking about rules in general, I will say this:
Rules can definitely be enforced if the people enforcing the rules actually want to enforce them.
For example, police can choose to set up speed traps and issue speeding tickets. Those tickets have to paid (or contested); they cannot be ignored. Police don't do this everywhere all the time (mostly because of resources).
Bringing it back to football: the NCAA has Harbaugh (and therefore Michigan) in their sights for two reasons:
1) He lied to them during in the recruiting violations investigation (NCAA doesn't take that lightly)
2) He keeps speaking up about making players employees (not saying he is wrong to do so, but the NCAA definitely doesn't like that).
As such, he (and therefore Michigan) are going to be the subject of a "speed trap".
The only wildcard would be if Harbaugh bolts for the NFL, will the NCAA lost their zeal to go after Michigan. I don't *think* so (given the outrage over their cheating) but we are in somewhat uncharted waters here.