Any coach that would pass on a player based on a bias of a rival college will never make it. Jim Harbaugh isn't a moron, if he needed a QB and CJ Stroud was the best on the board it wouldn't matter one bit that he is from Ohio State. Not one bit.
CJ Stroud is basically the most prolific passer in the history of one of the best programs in the history of the game of football. JT Barrett has a few more yards (1200) and a few more TDs (19) but over 400 more attempts.
That's a resume that deserves a shot. Every player is different. Should Saquon Barkley or Miles Sanders be judged on the fact Curtis Enis, KiJana Carter, DJ Dozier & Blair Thomas didn't work out?